We are so happy that WAPO published an article about the extremely interesting work being carried out by Dr Dina Dechmann, Dr Liliana Dávalos, and 2N Pharma CSO and Aalborg University associate prof. Dr John Dirk Vestergaard Nieland.
In the winter, the lipid-rich white matter of the shrew’s brain shrinks, only to regrow in the spring. In humans, the deterioration of white matter, which helps relay information in the brain, is a symptom of Alzheimer’s, Parkinson’s and other neurodegenerative diseases.
It is still unknown what triggers the shrinkage and regrowth in shrews, but if the mechanism is identified, it could potentially be a new pathway to treat or improve treatment of brain diseases. And there is a very nice link with 2N Pharma’s work to develop partial fatty acid oxidation inhibitors to address the cellular energy generation deficiency often seen in neurodegenerative diseases.
Read the full article here: